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KMID : 0357219960080010015
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Journal of Korean Society Physical Therapy
1996 Volume.8 No. 1 p.15 ~ p.20
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Naloxone Reversal of He-Ne Laser Stimulation Induced Analgesia in Rat
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Abstract
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The purpose of this study were to 1) determine the analgesic effect of 632.8 nm of helium-neon (He-Ne) laser stimulation on acupuncture point in rat and 2) determine the reversal of analgesic effect by naloxone injection. Eighteen Sprague-Dawley rats were devided into three groups : control (n=6) : laser (n=6), laser stimulation at 3.58;J/cm^2 ; and naloxone (n=6), 1 mg/kg of naloxone chloride inject into peritoneum before laser stimulation at 3.63J/cm^2. Tail-flick latency were measured pretreat and posttreat with hot plate (55^{circ}C). Data were analyzed using one-way ANOVA and paired t-teat for tail-flick latency. No significant change was noted in the tail-flick latency in either control or naloxone groups. But significant increased in tail-flick latency in taller group. The results suggest that He-Ne laser induced analgesic effect, and endogenous opioids may be involved in He-Ne laser induced analgesia.
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